Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:affiliatedWith |
class II aminoacyl-tRNA synthetases
|
| gptkbp:alternativeName |
ProRS
proline--tRNA ligase |
| gptkbp:biologicalProcess |
translator
aminoacyl-tRNA biosynthetic process |
| gptkbp:catalyzes |
attachment of proline to tRNA(Pro)
|
| gptkbp:EC_number |
6.1.1.15
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:function |
aminoacylation of tRNA(Pro)
|
| gptkbp:gene |
PARS2
|
| gptkbp:gene_symbol_(human_cytoplasmic) |
PARS1
|
| https://www.w3.org/2000/01/rdf-schema#label |
prolyl-tRNA synthetase
|
| gptkbp:inhibitedBy |
halofuginone
|
| gptkbp:molecular_function_(GO) |
proline-tRNA ligase activity
|
| gptkbp:product |
gptkb:AMP
pyrophosphate prolyl-tRNA(Pro) |
| gptkbp:requires |
protein synthesis
|
| gptkbp:structure |
homodimer (in many species)
|
| gptkbp:substrate |
gptkb:ATP
L-proline tRNA(Pro) |
| gptkbp:UniProt_ID_(human_cytoplasmic) |
gptkb:P49588
|
| gptkbp:UniProtID |
gptkb:Q6P2Q9
|
| gptkbp:bfsParent |
gptkb:class_II_aminoacyl-tRNA_synthetase
|
| gptkbp:bfsLayer |
7
|