primary progressive MS

GPTKB entity

Statements (27)
Predicate Object
gptkbp:instanceOf gptkb:disease
multiple sclerosis subtype
gptkbp:abbreviation gptkb:PPMS
gptkbp:affects central nervous system
gptkbp:causedBy unknown
gptkbp:firstDescribed 1970s
gptkbp:hasOnsetAge usually after age 40
https://www.w3.org/2000/01/rdf-schema#label primary progressive MS
gptkbp:offersCourse steady progression without relapses
gptkbp:prevalence about 10-15% of MS cases
gptkbp:prognosis generally worse than relapsing-remitting MS
gptkbp:riskFactor age
genetics
environmental factors
gptkbp:subspecies multiple sclerosis
gptkbp:symptom balance problems
muscle weakness
spasticity
bladder dysfunction
cognitive impairment
progressive neurological disability
walking difficulties
gptkbp:treatment gptkb:ocrelizumab
physical therapy
symptomatic management
gptkbp:bfsParent gptkb:Multiple_Sclerosis
gptkbp:bfsLayer 5