Multiple Sclerosis

GPTKB entity

Statements (53)
Predicate Object
gptkbp:instanceOf autoimmune disease
neurological disorder
gptkbp:affects central nervous system
gptkbp:associatedWith autoantibodies
oligoclonal bands in CSF
gptkbp:cause unknown
disability
gptkbp:characterizedBy inflammation
demyelination
neurodegeneration
gptkbp:commonIn gptkb:women
gptkbp:diagnosedBy clinical evaluation
MRI
evoked potentials
lumbar puncture
gptkbp:firstDescribed 1868
gptkbp:hasNoCure true
https://www.w3.org/2000/01/rdf-schema#label Multiple Sclerosis
gptkbp:ICD-10_code G35
gptkbp:MeSH_ID D009103
gptkbp:monitors MRI
gptkbp:namedFor gptkb:Jean-Martin_Charcot
gptkbp:OMIM 126200
gptkbp:onset young adults
20-40 years old
gptkbp:prevalence 2.8 million people worldwide
gptkbp:prognosis variable
gptkbp:researchInterest immunomodulation
remyelination
gptkbp:riskFactor gptkb:Epstein-Barr_virus_infection
smoking
genetic predisposition
vitamin D deficiency
gptkbp:symptom pain
fatigue
muscle weakness
spasticity
bladder dysfunction
cognitive impairment
difficulty with coordination
numbness
vision problems
gptkbp:treatment disease-modifying therapies
physical therapy
corticosteroids
immunosuppressants
symptomatic treatments
gptkbp:type gptkb:primary_progressive_MS
gptkb:progressive-relapsing_MS
gptkb:relapsing-remitting_MS
gptkb:secondary_progressive_MS
gptkbp:bfsParent gptkb:MS
gptkbp:bfsLayer 4