PPMS

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:Primary_Progressive_Multiple_Sclerosis
gptkbp:characterizedBy progressive neurological decline
gptkbp:diagnosedBy neurological examination
MRI
gptkbp:firstDescribed late 20th century
gptkbp:fullName gptkb:Primary_Progressive_Multiple_Sclerosis
https://www.w3.org/2000/01/rdf-schema#label PPMS
gptkbp:notableDifferenceFrom relapsing-remitting multiple sclerosis
gptkbp:onset usually after age 40
gptkbp:prevalence about 10-15% of MS cases
gptkbp:progression steady without relapses
gptkbp:symptom balance problems
muscle weakness
spasticity
bladder dysfunction
walking difficulties
gptkbp:treatment gptkb:ocrelizumab
physical therapy
symptomatic management
gptkbp:type multiple sclerosis
gptkbp:bfsParent gptkb:primary_progressive_MS
gptkbp:bfsLayer 6