primary aldosteronism

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:affects adrenal glands
gptkbp:alsoKnownAs gptkb:Conn's_syndrome
gptkbp:cause hypertension
hypokalemia
adrenal adenoma
bilateral adrenal hyperplasia
gptkbp:characterizedBy excess production of aldosterone
gptkbp:complication gptkb:cardiovascular_disease
stroke
kidney damage
gptkbp:diagnosedBy adrenal imaging
aldosterone-renin ratio
saline infusion test
gptkbp:firstDescribed gptkb:Jerome_W._Conn
1955
https://www.w3.org/2000/01/rdf-schema#label primary aldosteronism
gptkbp:ICD-10_code E26.0
gptkbp:prevalence 5-10% of hypertensive patients
gptkbp:riskFactor genetic mutations
family history of hypertension
gptkbp:symptom fatigue
headache
muscle weakness
polydipsia
polyuria
gptkbp:treatment gptkb:spironolactone
gptkb:eplerenone
surgery
mineralocorticoid receptor antagonists
gptkbp:bfsParent gptkb:Renin-angiotensin_system
gptkbp:bfsLayer 6