Statements (35)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | gptkb:disease | 
| gptkbp:affects | adrenal glands | 
| gptkbp:alsoKnownAs | gptkb:Conn's_syndrome | 
| gptkbp:cause | hypertension hypokalemia adrenal adenoma bilateral adrenal hyperplasia | 
| gptkbp:characterizedBy | excess production of aldosterone | 
| gptkbp:complication | gptkb:cardiovascular_disease stroke kidney damage | 
| gptkbp:diagnosedBy | adrenal imaging aldosterone-renin ratio saline infusion test | 
| gptkbp:firstDescribed | gptkb:Jerome_W._Conn 1955 | 
| gptkbp:ICD-10_code | E26.0 | 
| gptkbp:prevalence | 5-10% of hypertensive patients | 
| gptkbp:riskFactor | genetic mutations family history of hypertension | 
| gptkbp:symptom | fatigue headache muscle weakness polydipsia polyuria | 
| gptkbp:treatment | gptkb:spironolactone gptkb:eplerenone surgery mineralocorticoid receptor antagonists | 
| gptkbp:bfsParent | gptkb:KCNJ5 gptkb:Renin-angiotensin_system gptkb:angiotensin_receptor_blockers gptkb:Jerome_W._Conn | 
| gptkbp:bfsLayer | 8 | 
| https://www.w3.org/2000/01/rdf-schema#label | primary aldosteronism |