potassium-chloride cotransporter
GPTKB entity
Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:dysregulationAssociatedWith |
gptkb:hereditary_spastic_paraplegia
epilepsy peripheral neuropathy |
| gptkbp:encodedBy |
gptkb:SLC12A5
gptkb:SLC12A6 SLC12A4 SLC12A7 |
| gptkbp:foundIn |
gptkb:cell_membrane
|
| gptkbp:function |
transports potassium and chloride ions across cell membranes
|
| https://www.w3.org/2000/01/rdf-schema#label |
potassium-chloride cotransporter
|
| gptkbp:importantFor |
cell volume regulation
neuronal chloride homeostasis |
| gptkbp:inhibitedBy |
furosemide
bumetanide |
| gptkbp:memberOf |
gptkb:solute_carrier_family
|
| gptkbp:proteinFamily |
SLC12
|
| gptkbp:relatedTo |
gptkb:GABAergic_signaling
|
| gptkbp:type |
gptkb:KCC2
KCC1 KCC3 KCC4 |
| gptkbp:bfsParent |
gptkb:SLC12A5
|
| gptkbp:bfsLayer |
8
|