Statements (56)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:healthcare_organization
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:microscopic_polyangiitis
|
| gptkbp:affects |
medium-sized muscular arteries
|
| gptkbp:associated_with |
gptkb:hepatitis_B_virus
|
| gptkbp:caused_by |
immune system dysfunction
|
| gptkbp:clinical_trial |
treatment efficacy
ongoing studies new therapies cardiac involvement cutaneous manifestations gastrointestinal involvement renal involvement mononeuritis multiplex |
| gptkbp:code |
446.0
M30.0 |
| gptkbp:complications |
heart problems
kidney damage nerve damage skin ulcers |
| gptkbp:current_use |
systemic vasculitis
|
| gptkbp:first_described_by |
in the 19th century
|
| gptkbp:gender |
more common in males
|
| gptkbp:historical_significance |
first described by Kussmaul and Maier
important in rheumatology |
| https://www.w3.org/2000/01/rdf-schema#label |
polyarteritis nodosa
|
| gptkbp:is_a_route_for |
inflammation of blood vessels
immune-mediated damage necrotizing vasculitis |
| gptkbp:population |
adults
age range 30-60 more prevalent in certain ethnic groups |
| gptkbp:premiered_on |
adulthood
|
| gptkbp:research_focus |
treatment outcomes
pathogenesis long-term prognosis |
| gptkbp:social_responsibility |
gptkb:granulomatosis_with_polyangiitis
gptkb:Takayasu_arteritis gptkb:Churg-Strauss_syndrome gptkb:healthcare_organization gptkb:rheumatoid_arthritis biopsy rare disease depends on severity variable outcomes early treatment improves outcomes |
| gptkbp:symptoms |
muscle pain
weight loss abdominal pain fever joint pain |
| gptkbp:treatment |
corticosteroids
remission possible immunosuppressive drugs long-term follow-up necessary relapses common |