|
gptkbp:instanceOf
|
gptkb:chemical_compound
gptkb:drug
gptkb:vitamin_A
|
|
gptkbp:alsoKnownAs
|
gptkb:phylloquinone
gptkb:vitamin_A
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
B02BA01
|
|
gptkbp:boilingPoint
|
> 450 °C
|
|
gptkbp:CASNumber
|
84-80-0
|
|
gptkbp:chemicalFormula
|
C31H46O2
|
|
gptkbp:color
|
yellow
|
|
gptkbp:contraindication
|
hypersensitivity to vitamin K1
|
|
gptkbp:discoveredIn
|
1930s
|
|
gptkbp:eliminationHalfLife
|
1.5–3 hours
|
|
gptkbp:firstIsolatedFrom
|
alfalfa
|
|
gptkbp:firstSynthesized
|
gptkb:Paul_Karrer
|
|
gptkbp:foundIn
|
green leafy vegetables
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
phytomenadione
|
|
gptkbp:IUPACName
|
gptkb:2-methyl-3-phytyl-1,4-naphthoquinone
|
|
gptkbp:legalStatus
|
OTC (US)
Rx-only (UK)
|
|
gptkbp:meltingPoint
|
5 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
450.7 g/mol
|
|
gptkbp:notableFor
|
preventing hemorrhagic disease of the newborn
|
|
gptkbp:nutrient
|
animals
humans
|
|
gptkbp:pregnancyCategory
|
A (oral)
C (parenteral)
|
|
gptkbp:producedBy
|
plants
|
|
gptkbp:PubChem_CID
|
5280483
|
|
gptkbp:relatedTo
|
gptkb:menaquinone_(vitamin_K2)
menadione (vitamin K3)
|
|
gptkbp:role
|
blood clotting
synthesis of clotting factors II, VII, IX, X
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
subcutaneous
intravenous
|
|
gptkbp:sideEffect
|
allergic reactions
injection site reactions
flushing
|
|
gptkbp:solubility
|
fat-soluble
|
|
gptkbp:UNII
|
A034SE7857
|
|
gptkbp:usedFor
|
treatment of vitamin K deficiency
reversal of anticoagulant effects of warfarin
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
yes
|
|
gptkbp:bfsParent
|
gptkb:2-methyl-3-phytyl-1,4-naphthoquinone_(K1)
|
|
gptkbp:bfsLayer
|
5
|