|
gptkbp:instanceOf
|
gptkb:chemical_compound
antihistamine
|
|
gptkbp:ATCCode
|
R06AC03
|
|
gptkbp:CASNumber
|
86-21-5
|
|
gptkbp:category
|
gptkb:WHO_essential_medicine
over-the-counter drug
alkylamine antihistamine
|
|
gptkbp:contraindication
|
asthma
severe hypertension
severe coronary artery disease
prostatic hypertrophy
narrow angle glaucoma
|
|
gptkbp:discoveredBy
|
gptkb:Roche
|
|
gptkbp:discoveredIn
|
1948
|
|
gptkbp:drugClass
|
first-generation antihistamine
|
|
gptkbp:eliminationHalfLife
|
16-19 hours
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:hasMolecularFormula
|
C16H20N2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
pheniramine
|
|
gptkbp:interactsWith
|
gptkb:beer
gptkb:MAO_inhibitors
gptkb:CNS_depressants
|
|
gptkbp:legalStatus
|
OTC (in some countries)
|
|
gptkbp:mechanismOfAction
|
H1 receptor antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
C (US)
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
dizziness
blurred vision
drowsiness
dry mouth
urinary retention
|
|
gptkbp:synonym
|
Avil
Phenargan
|
|
gptkbp:usedFor
|
gptkb:hay_fever
pruritus
allergic rhinitis
urticaria
allergic conditions
common cold symptoms
|
|
gptkbp:bfsParent
|
gptkb:Visine
|
|
gptkbp:bfsLayer
|
7
|