bullous pemphigoid

GPTKB entity

Statements (48)
Predicate Object
gptkbp:instanceOf gptkb:skin
autoimmune disease
gptkbp:affects gptkb:skin
elderly
gptkbp:antibodyTarget BP230
BP180
gptkbp:associatedWith gptkb:DST
COL17A1
gptkbp:causedBy autoantibodies
gptkbp:complication sepsis
dehydration
secondary infection
gptkbp:diagnosedBy serology
skin biopsy
direct immunofluorescence
gptkbp:differentialDiagnosis gptkb:pemphigus_vulgaris
gptkb:epidermolysis_bullosa_acquisita
dermatitis herpetiformis
gptkbp:firstDescribed 1953
gptkbp:hasEpidemiology slightly more common in males
more common in elderly
gptkbp:hasOrphanetID ORPHA:792
gptkbp:hasUMLSID C0006287
https://www.w3.org/2000/01/rdf-schema#label bullous pemphigoid
gptkbp:ICD-10_code L12.0
gptkbp:MeSH_ID D001769
gptkbp:mortalityRate low
gptkbp:offersCourse chronic
relapsing
gptkbp:OMIM 112190
gptkbp:pathology subepidermal blister
gptkbp:prevalence rare
gptkbp:prognosis good with treatment
can be fatal if untreated
gptkbp:riskFactor older age
neurological disease
use of certain medications
gptkbp:symptom itching
erythema
blistering
urticaria-like lesions
gptkbp:treatment gptkb:dapsone
corticosteroids
immunosuppressants
topical steroids
tetracyclines
gptkbp:bfsParent gptkb:sitagliptin
gptkbp:bfsLayer 6