papain-like protease

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:enzyme
gptkbp:alternativeName gptkb:PLP
PLpro
gptkbp:biologicalProcess deubiquitinating enzyme
ubiquitin-specific protease activity
deISGylating enzyme
gptkbp:encodedBy coronavirus genome
gptkbp:enzymeClassification EC 3.4.22
gptkbp:foundIn gptkb:COVID-19
gptkb:MERS-CoV
gptkb:SARS-CoV
gptkbp:function cleaves viral polyprotein
antagonizes host immune response
gptkbp:hasActivity cysteine protease activity
https://www.w3.org/2000/01/rdf-schema#label papain-like protease
gptkbp:inhibitedBy GRL-0617
VIR250
gptkbp:structure papain-like fold
contains catalytic triad
gptkbp:target antiviral drug research
gptkbp:bfsParent gptkb:SARS-CoV-2_virion
gptkbp:bfsLayer 7