Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
gptkb:enzyme |
gptkbp:alternativeName |
gptkb:PLP
PLpro |
gptkbp:biologicalProcess |
deubiquitinating enzyme
ubiquitin-specific protease activity deISGylating enzyme |
gptkbp:encodedBy |
coronavirus genome
|
gptkbp:enzymeClassification |
EC 3.4.22
|
gptkbp:foundIn |
gptkb:COVID-19
gptkb:MERS-CoV gptkb:SARS-CoV |
gptkbp:function |
cleaves viral polyprotein
antagonizes host immune response |
gptkbp:hasActivity |
cysteine protease activity
|
https://www.w3.org/2000/01/rdf-schema#label |
papain-like protease
|
gptkbp:inhibitedBy |
GRL-0617
VIR250 |
gptkbp:structure |
papain-like fold
contains catalytic triad |
gptkbp:target |
antiviral drug research
|
gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
gptkbp:bfsLayer |
7
|