Statements (63)
Predicate | Object |
---|---|
gptkbp:instance_of |
gptkb:protein
|
gptkbp:associated_with |
wound healing
bone development |
gptkbp:code |
SPARC gene
|
gptkbp:function |
binds to collagen
regulates mineralization |
gptkbp:has_binding_site_for |
calcium ions
|
gptkbp:has_role |
angiogenesis
|
https://www.w3.org/2000/01/rdf-schema#label |
osteonectin
|
gptkbp:involved_in |
tissue repair
cell adhesion |
gptkbp:is_associated_with |
gptkb:neurodegenerative_diseases
chronic pain fibrosis chronic inflammation cell migration metastasis |
gptkbp:is_expressed_in |
gptkb:Skin
gptkb:Heart gptkb:embryonic_development placenta various tissues kidneys lungs adipose tissue |
gptkbp:is_found_in |
cartilage
human body |
gptkbp:is_involved_in |
cell differentiation
cell proliferation cellular stress response immune response metabolic processes tissue engineering cell signaling pathways extracellular matrix remodeling vascular remodeling tumor progression bone remodeling neovascularization muscle repair neural repair mineral homeostasis angiogenic processes fibroblast activity |
gptkbp:is_linked_to |
gptkb:diabetes
age-related diseases autoimmune diseases chronic diseases inflammation cardiovascular diseases osteoporosis |
gptkbp:is_part_of |
bone matrix
|
gptkbp:is_regulated_by |
transforming growth factor beta
|
gptkbp:is_related_to |
extracellular matrix proteins
|
gptkbp:is_studied_for |
therapeutic applications
biomaterials development |
gptkbp:is_studied_in |
cancer research
regenerative medicine |
gptkbp:is_used_in |
biomarker studies
|
gptkbp:location |
extracellular matrix
|
gptkbp:produced_by |
osteoblasts
|
gptkbp:bfsParent |
gptkb:SPARC_family
|
gptkbp:bfsLayer |
7
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