Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:cleavage |
viral protease
pp1a polyprotein |
| gptkbp:conservedAmong |
betacoronaviruses
|
| gptkbp:encodedBy |
coronavirus genome
|
| gptkbp:foundIn |
gptkb:COVID-19
gptkb:MERS-CoV gptkb:SARS-CoV |
| gptkbp:fullName |
non-structural protein 6
|
| gptkbp:function |
induces autophagosome formation
involved in viral replication complex formation restricts autophagosome expansion |
| gptkbp:geneOrderInGenome |
ORF1a polyprotein
|
| https://www.w3.org/2000/01/rdf-schema#label |
nsp6
|
| gptkbp:interactsWith |
gptkb:nsp3
gptkb:nsp4 |
| gptkbp:length |
290
|
| gptkbp:locale |
endoplasmic reticulum membrane
|
| gptkbp:mutationAssociatedWith |
gptkb:Delta_variant
gptkb:Omicron_variant |
| gptkbp:roleInPathogenesis |
contributes to immune evasion
modulates host cell autophagy |
| gptkbp:transmembraneDomains |
6
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
| gptkbp:bfsLayer |
7
|