Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:cleavage |
polyprotein 1a/1ab
|
| gptkbp:conservedIn |
coronaviridae
|
| gptkbp:encodedBy |
coronavirus genome
|
| gptkbp:foundIn |
gptkb:COVID-19
gptkb:MERS-CoV gptkb:SARS-CoV |
| gptkbp:fullName |
non-structural protein 4
|
| gptkbp:function |
formation of double-membrane vesicles
membrane rearrangement |
| gptkbp:geneOrder |
ORF1a polyprotein
|
| https://www.w3.org/2000/01/rdf-schema#label |
nsp4
|
| gptkbp:interactsWith |
gptkb:nsp3
gptkb:nsp6 |
| gptkbp:length |
500-600 amino acids (varies by virus)
|
| gptkbp:locale |
gptkb:endoplasmic_reticulum
|
| gptkbp:mutationAssociatedWith |
impairs viral replication
|
| gptkbp:requires |
virus replication
|
| gptkbp:role |
viral replication complex
|
| gptkbp:structure |
multi-pass transmembrane protein
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
| gptkbp:bfsLayer |
7
|