Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:cleavage |
gptkb:ORF1ab_polyprotein
|
| gptkbp:conservedIn |
coronaviruses
|
| gptkbp:domain |
polymerase domain
NiRAN domain |
| gptkbp:encodedBy |
gptkb:COVID-19
|
| gptkbp:enzymeCommissionNumber |
2.7.7.48
|
| gptkbp:expressedIn |
infected host cells
|
| gptkbp:fullName |
non-structural protein 12
|
| gptkbp:function |
RNA-dependent RNA polymerase
|
| https://www.w3.org/2000/01/rdf-schema#label |
nsp12
|
| gptkbp:inhibitedBy |
gptkb:remdesivir
|
| gptkbp:interactsWith |
gptkb:nsp7
gptkb:nsp8 |
| gptkbp:locatedOnChromosome |
gptkb:ORF1ab_polyprotein
|
| gptkbp:molecularWeight |
~106 kDa
|
| gptkbp:PDB |
6M71
7BV2 |
| gptkbp:requires |
SARS-CoV-2 replication
|
| gptkbp:roleInVirus |
viral genome replication
|
| gptkbp:target |
antiviral drugs
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
| gptkbp:bfsLayer |
7
|