nsp10

GPTKB entity

Statements (26)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:encodedBy orf1ab polyprotein
gptkbp:foundIn gptkb:COVID-19
gptkb:MERS-CoV
gptkb:SARS-CoV
coronaviruses
gptkbp:fullName non-structural protein 10
gptkbp:function stimulates 2'-O-methyltransferase activity of nsp16
cofactor for nsp14
cofactor for nsp16
stimulates exoribonuclease activity of nsp14
https://www.w3.org/2000/01/rdf-schema#label nsp10
gptkbp:interactsWith gptkb:nsp14
gptkb:nsp16
gptkbp:length 139 amino acids (SARS-CoV-2)
gptkbp:locatedOnChromosome orf1ab region
gptkbp:molecularWeight 15.6 kDa (SARS-CoV-2)
gptkbp:PDB 6W4H
6ZCT
gptkbp:requires viral replication
gptkbp:roleInVirus immune evasion
RNA cap modification
proofreading of viral RNA
gptkbp:structure contains two zinc finger motifs
gptkbp:bfsParent gptkb:SARS-CoV-2_virion
gptkbp:bfsLayer 7