Statements (26)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:encodedBy |
orf1ab polyprotein
|
gptkbp:foundIn |
gptkb:COVID-19
gptkb:MERS-CoV gptkb:SARS-CoV coronaviruses |
gptkbp:fullName |
non-structural protein 10
|
gptkbp:function |
stimulates 2'-O-methyltransferase activity of nsp16
cofactor for nsp14 cofactor for nsp16 stimulates exoribonuclease activity of nsp14 |
https://www.w3.org/2000/01/rdf-schema#label |
nsp10
|
gptkbp:interactsWith |
gptkb:nsp14
gptkb:nsp16 |
gptkbp:length |
139 amino acids (SARS-CoV-2)
|
gptkbp:locatedOnChromosome |
orf1ab region
|
gptkbp:molecularWeight |
15.6 kDa (SARS-CoV-2)
|
gptkbp:PDB |
6W4H
6ZCT |
gptkbp:requires |
viral replication
|
gptkbp:roleInVirus |
immune evasion
RNA cap modification proofreading of viral RNA |
gptkbp:structure |
contains two zinc finger motifs
|
gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
gptkbp:bfsLayer |
7
|