Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
host shutoff factor
|
| gptkbp:block |
host mRNA translation
|
| gptkbp:determines |
gptkb:cryo-EM
X-ray crystallography |
| gptkbp:encodedBy |
ORF1a
|
| gptkbp:firstDescribed |
2003
|
| gptkbp:foundIn |
gptkb:COVID-19
gptkb:SARS-CoV coronaviruses |
| gptkbp:fullName |
non-structural protein 1
|
| gptkbp:function |
inhibits host immune response
suppresses host gene expression |
| https://www.w3.org/2000/01/rdf-schema#label |
nsp1
|
| gptkbp:interactsWith |
40S ribosomal subunit
|
| gptkbp:length |
180 amino acids (SARS-CoV-2)
|
| gptkbp:orthologIn |
nsp1 of other betacoronaviruses
|
| gptkbp:promotion |
host mRNA degradation
|
| gptkbp:target |
antiviral research
|
| gptkbp:bfsParent |
gptkb:SARS-CoV-2_virion
|
| gptkbp:bfsLayer |
7
|