Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:antibiotic
|
| gptkbp:ATCCode |
J01XX06
|
| gptkbp:CASNumber |
1476-53-5
|
| gptkbp:category |
natural product
aminocoumarin antibiotic bacterial DNA replication inhibitor |
| gptkbp:discoveredBy |
gptkb:Herbert_E._Carter
gptkb:Karl_Folkers |
| gptkbp:discoveredIn |
1955
|
| gptkbp:hasMolecularFormula |
C31H36N2O11
|
| https://www.w3.org/2000/01/rdf-schema#label |
novobiocin
|
| gptkbp:legalStatus |
withdrawn in US
|
| gptkbp:mechanismOfAction |
inhibits DNA gyrase
|
| gptkbp:molecularWeight |
612.63 g/mol
|
| gptkbp:producedBy |
Streptomyces niveus
|
| gptkbp:routeOfAdministration |
oral
topical |
| gptkbp:sideEffect |
nausea
vomiting rash |
| gptkbp:target |
bacterial DNA gyrase
|
| gptkbp:usedFor |
gptkb:antibiotic
|
| gptkbp:usedIn |
novobiocin test
|
| gptkbp:usedToDistinguish |
gptkb:Staphylococcus_epidermidis
gptkb:Staphylococcus_saprophyticus |
| gptkbp:bfsParent |
gptkb:DNA_gyrase
|
| gptkbp:bfsLayer |
6
|