|
gptkbp:instanceOf
|
gptkb:drug
synthetic progestogen
|
|
gptkbp:ATCCode
|
G03AC01
|
|
gptkbp:brand
|
gptkb:Noriday
Aygestin
Micronor
Primolut N
|
|
gptkbp:CASNumber
|
68-22-4
|
|
gptkbp:category
|
gptkb:Corticosteroid
hormonal contraceptive
progestin
World Health Organization essential medicine
|
|
gptkbp:contraindication
|
gptkb:liver_disease
pregnancy
history of thrombosis
|
|
gptkbp:developedBy
|
gptkb:Carl_Djerassi
gptkb:George_Rosenkranz
Luis Miramontes
|
|
gptkbp:discoveredBy
|
gptkb:Syntex
|
|
gptkbp:discoveredIn
|
1951
|
|
gptkbp:eliminationHalfLife
|
5-12 hours
|
|
gptkbp:hasMolecularFormula
|
C20H26O2
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
norethisterone
|
|
gptkbp:IUPACName
|
17α-ethynyl-17β-hydroxyestr-4-en-3-one
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:marketedAs
|
1957
|
|
gptkbp:mechanismOfAction
|
suppresses ovulation
progestogenic activity
|
|
gptkbp:meltingPoint
|
205–206 °C
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
X (contraindicated)
|
|
gptkbp:PubChem_CID
|
6230
DB00717
|
|
gptkbp:relatedTo
|
gptkb:levonorgestrel
gptkb:norethynodrel
ethinylestradiol
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular injection
|
|
gptkbp:sideEffect
|
nausea
headache
breast tenderness
mood changes
weight gain
|
|
gptkbp:UNII
|
4X6E73CJ0Q
|
|
gptkbp:usedFor
|
contraception
hormone replacement therapy
endometriosis
treatment of menstrual disorders
delay of menstruation
|
|
gptkbp:bfsParent
|
gptkb:medroxyprogesterone_acetate
gptkb:G03GA04
gptkb:G03GA09
gptkb:Estrogen-progestogen_oral_contraceptives
|
|
gptkbp:bfsLayer
|
7
|