medroxyprogesterone acetate

URI: https://gptkb.org/entity/medroxyprogesterone_acetate
GPTKB entity
Statements (51)
Predicate Object
gptkbp:instanceOf synthetic progestin
hormonal medication
gptkbp:ATCCode gptkb:G03AC06
gptkbp:brand gptkb:Depo-Provera
gptkb:Depo-SubQ_Provera_104
Provera
gptkbp:CASNumber gptkb:71-58-9
gptkbp:contraindication pregnancy
liver dysfunction
known or suspected breast cancer
active thromboembolic disorders
gptkbp:discoveredBy gptkb:Upjohn
gptkbp:eliminationHalfLife 40-60 hours (oral)
6-7 days (IM)
gptkbp:genericName yes
gptkbp:hasMolecularFormula C24H34O4
https://www.w3.org/2000/01/rdf-schema#label medroxyprogesterone acetate
gptkbp:introducedIn 1957
gptkbp:IUPACName gptkb:17α-acetoxy-6α-methylprogesterone
gptkbp:KEGGID gptkb:D00429
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction inhibition of gonadotropin secretion
progestogenic activity
suppression of ovulation
gptkbp:metabolism liver
gptkbp:pregnancyCategory gptkb:X_(US)
gptkbp:PubChem_CID gptkb:CHEMBL1391
gptkb:DB00603
6377
6626
gptkbp:relatedTo gptkb:progesterone
gptkb:megestrol_acetate
gptkb:norethisterone
gptkbp:routeOfAdministration oral
intramuscular injection
subcutaneous injection
gptkbp:sideEffect abdominal pain
headache
weight gain
nervousness
decreased bone density
menstrual irregularities
gptkbp:UNII 8C5M2VZ4RQ
gptkbp:usedFor contraception
hormone replacement therapy
treatment of certain cancers
treatment of endometriosis
treatment of abnormal uterine bleeding
treatment of amenorrhea
gptkbp:bfsParent gptkb:Sayana_Press
gptkbp:bfsLayer 6