non-transfusion-dependent thalassemia

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:medical_condition gptkb:anemia
gptkbp:alternativeName	gptkb:NTDT mild thalassemia
gptkbp:causedBy	mutation in HBB gene mutation in HBA1 gene mutation in HBA2 gene
gptkbp:complication	gptkb:bone pulmonary hypertension gallstones iron overload leg ulcers
gptkbp:distinctFrom	gptkb:transfusion-dependent_thalassemia
gptkbp:hasDiagnosticMethod	genetic testing complete blood count hemoglobin electrophoresis
gptkbp:inheritance	autosomal recessive
gptkbp:onset	childhood
gptkbp:prevalence	higher in Mediterranean, Middle Eastern, South Asian, and Southeast Asian populations
gptkbp:subspecies	gptkb:hemoglobin_E/beta-thalassemia gptkb:alpha-thalassemia_(HbH_disease) gptkb:beta-thalassemia_intermedia
gptkbp:symptom	gptkb:anemia fatigue jaundice splenomegaly
gptkbp:treatment	gptkb:hydroxyurea folic acid supplementation iron chelation therapy blood transfusion (occasional)
gptkbp:bfsParent	gptkb:Exjade
gptkbp:bfsLayer	7
https://www.w3.org/2000/01/rdf-schema#label	non-transfusion-dependent thalassemia