Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abnormalAccumulationAssociatedWith |
gptkb:Alzheimer's_disease
gptkb:Parkinson's_disease amyotrophic lateral sclerosis |
| gptkbp:component |
neuronal cytoskeleton
|
| gptkbp:discoveredBy |
gptkb:Pasko_Rakic
|
| gptkbp:foundIn |
neurons
|
| gptkbp:function |
structural support
maintenance of axon caliber |
| gptkbp:gene |
gptkb:NEFL
NEFH NEFM |
| gptkbp:hasBiomarker |
neurodegenerative diseases
|
| https://www.w3.org/2000/01/rdf-schema#label |
neurofilament proteins
|
| gptkbp:location |
axon
neuronal cell body |
| gptkbp:molecularWeight |
60-200 kDa
|
| gptkbp:phosphorylates |
gptkb:axonal_transport
neuronal stability |
| gptkbp:subunit |
peripherin
NF-H NF-L NF-M α-internexin |
| gptkbp:type |
intermediate filament protein
|
| gptkbp:bfsParent |
gptkb:Cytoskeleton
|
| gptkbp:bfsLayer |
7
|