neurofilament light chain (NfL)
GPTKB entity
Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:abbreviation |
NfL
|
| gptkbp:component |
neurofilament
|
| gptkbp:elevatedIn |
gptkb:Parkinson's_disease
gptkb:trauma gptkb:Huntington's_disease axonal injury |
| gptkbp:encodedBy |
NEFL gene
|
| gptkbp:foundIn |
neurons
|
| gptkbp:function |
maintains neuronal caliber
supports axonal transport |
| gptkbp:hasBiomarker |
gptkb:Alzheimer's_disease
amyotrophic lateral sclerosis multiple sclerosis neurodegenerative diseases |
| https://www.w3.org/2000/01/rdf-schema#label |
neurofilament light chain (NfL)
|
| gptkbp:location |
axon cytoskeleton
|
| gptkbp:measures |
blood
cerebrospinal fluid |
| gptkbp:molecularWeight |
68 kDa
|
| gptkbp:structure |
intermediate filament protein
|
| gptkbp:bfsParent |
gptkb:Simoa_technology
gptkb:Single_Molecule_Array_(Simoa) |
| gptkbp:bfsLayer |
7
|