mouse Lrrk2

GPTKB entity

Statements (20)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:associatedWith Parkinson's disease (in model studies)
gptkbp:encodes leucine-rich repeat serine/threonine-protein kinase 2
gptkbp:Entrez_Gene_ID 66725
ENSMUSG00000036273
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
brain
gptkbp:function GTPase activity
protein kinase activity
gptkbp:gene Lrrk2
https://www.w3.org/2000/01/rdf-schema#label mouse Lrrk2
gptkbp:locatedOnChromosome mouse chromosome 15
gptkbp:mutationAssociatedWith affects dopaminergic neurons
used in Parkinson's disease models
gptkbp:organism gptkb:Mus_musculus
gptkbp:orthologIn human LRRK2
gptkbp:UniProtID gptkb:Q5S007
gptkbp:bfsParent gptkb:LRRK2
gptkbp:bfsLayer 7