Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
adjuvant
lipid A derivative |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:CASNumber |
72063-39-9
|
| gptkbp:component |
AS01 adjuvant system
AS04 adjuvant system |
| gptkbp:derivedFrom |
lipopolysaccharide
Salmonella minnesota |
| gptkbp:discoveredBy |
Ribi ImmunoChem Research
|
| gptkbp:hasImmunostimulatoryEffect |
yes
|
| gptkbp:hasLowerToxicityThan |
gptkb:lipid_A
|
| gptkbp:hasMolecularFormula |
C95H179N2O28P
|
| https://www.w3.org/2000/01/rdf-schema#label |
monophosphoryl lipid A
|
| gptkbp:modifiesImmuneResponse |
Th1-biased
|
| gptkbp:promotion |
gptkb:Toll-like_receptor_4
|
| gptkbp:routeOfAdministration |
intramuscular
|
| gptkbp:synonym |
gptkb:MPL
3-O-desacyl-4'-monophosphoryl lipid A |
| gptkbp:usedFor |
enhancing vaccine efficacy
|
| gptkbp:usedIn |
gptkb:Shingrix
gptkb:Cervarix vaccines |
| gptkbp:bfsParent |
gptkb:Cervarix
|
| gptkbp:bfsLayer |
6
|