microsatellite instability-high cancer
GPTKB entity
Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
cancer subtype
|
| gptkbp:associatedWith |
defective DNA mismatch repair
|
| gptkbp:characteristic |
microsatellite instability
|
| gptkbp:commonIn |
gptkb:endometrial_cancer
colorectal cancer gastric cancer |
| gptkbp:detects |
next-generation sequencing
PCR testing |
| gptkbp:hasBiomarker |
immunotherapy response
|
| https://www.w3.org/2000/01/rdf-schema#label |
microsatellite instability-high cancer
|
| gptkbp:mutationAssociatedWith |
gptkb:MLH1
gptkb:MSH2 gptkb:MSH6 gptkb:PMS2 gptkb:EPCAM |
| gptkbp:prognosis |
better prognosis in some cancers
|
| gptkbp:relatedTo |
gptkb:Lynch_syndrome
|
| gptkbp:response |
immune checkpoint inhibitors
|
| gptkbp:synonym |
gptkb:MSI-H_cancer
|
| gptkbp:bfsParent |
gptkb:Keytruda
|
| gptkbp:bfsLayer |
5
|