Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antibiotic class
|
| gptkbp:ATCCode |
J01FF
|
| gptkbp:binds |
50S ribosomal subunit
|
| gptkbp:contraindication |
history of colitis
|
| gptkbp:derivedFrom |
Streptomyces lincolnensis
|
| gptkbp:discoveredIn |
1960s
|
| gptkbp:example |
gptkb:lincomycin
gptkb:clindamycin |
| https://www.w3.org/2000/01/rdf-schema#label |
lincosamides
|
| gptkbp:mechanismOfAction |
inhibit bacterial protein synthesis
|
| gptkbp:pregnancyCategory |
B (clindamycin)
|
| gptkbp:resistantTo |
methylation of 23S rRNA
|
| gptkbp:routeOfAdministration |
oral
topical intravenous |
| gptkbp:sideEffect |
gptkb:pseudomembranous_colitis
|
| gptkbp:spectrumOfActivity |
anaerobic bacteria
gram-positive bacteria |
| gptkbp:usedFor |
treatment of bacterial infections
|
| gptkbp:bfsParent |
gptkb:23S_rRNA
|
| gptkbp:bfsLayer |
6
|