Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
eicosanoid
lipid mediator |
| gptkbp:antagonistDrug |
gptkb:pranlukast
gptkb:zafirlukast gptkb:montelukast |
| gptkbp:biosynthesisEnzyme |
5-lipoxygenase
|
| gptkbp:derivedFrom |
gptkb:arachidonic_acid
|
| gptkbp:function |
attract neutrophils
increase vascular permeability induce bronchoconstriction mediate inflammation |
| https://www.w3.org/2000/01/rdf-schema#label |
leukotrienes
|
| gptkbp:inhibitedBy |
corticosteroids
leukotriene receptor antagonists |
| gptkbp:predecessor |
5-HPETE
|
| gptkbp:recipient |
leukotriene receptor
|
| gptkbp:role |
asthma
anaphylaxis allergic rhinitis |
| gptkbp:subclassOf |
gptkb:LTC4
LTD4 LTE4 LTB4 |
| gptkbp:synthesisType |
gptkb:leukocytes
gptkb:mast_cells macrophages |
| gptkbp:bfsParent |
gptkb:arachidonic_acid
gptkb:omega-6 gptkb:basophil |
| gptkbp:bfsLayer |
7
|