Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:affiliatedWith |
class I aminoacyl-tRNA synthetases
|
| gptkbp:alternativeName |
LeuRS
leucine--tRNA ligase |
| gptkbp:associatedWith |
Charcot-Marie-Tooth disease (some forms)
|
| gptkbp:biologicalProcess |
leucine-tRNA ligase activity
|
| gptkbp:catalyzes |
attachment of leucine to tRNA(Leu)
|
| gptkbp:EC_number |
6.1.1.4
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
| gptkbp:function |
aminoacylation of tRNA(Leu)
|
| gptkbp:gene |
gptkb:LARS
|
| gptkbp:gene_symbol_(yeast) |
LEU1
|
| gptkbp:GO_term |
GO:0004823
|
| https://www.w3.org/2000/01/rdf-schema#label |
leucyl-tRNA synthetase
|
| gptkbp:inhibitedBy |
gptkb:tavaborole
|
| gptkbp:location |
gptkb:cytoplasm
mitochondria |
| gptkbp:PDB |
1WZ2
|
| gptkbp:product |
gptkb:AMP
pyrophosphate leucyl-tRNA(Leu) |
| gptkbp:requires |
protein biosynthesis
|
| gptkbp:structure |
homodimer
|
| gptkbp:substrate |
gptkb:ATP
leucine tRNA(Leu) |
| gptkbp:UniProtID |
Q15031
|
| gptkbp:bfsParent |
gptkb:class_I_aminoacyl-tRNA_synthetase
|
| gptkbp:bfsLayer |
7
|