isoleucyl-tRNA synthetase

URI: https://gptkb.org/entity/isoleucyl-tRNA_synthetase
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:affiliatedWith aminoacyl-tRNA synthetase family
gptkbp:alternativeName IleRS
isoleucine--tRNA ligase
gptkbp:biologicalProcess translator
isoleucine-tRNA ligase activity
gptkbp:catalyzes attachment of isoleucine to tRNA(Ile)
gptkbp:cellularComponent gptkb:cytoplasm
gptkbp:EC_number 6.1.1.5
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function aminoacylation of tRNA with isoleucine
gptkbp:gene IARS
gptkbp:gene_symbol_(E._coli) ileS
gptkbp:has_proofreading_activity yes
https://www.w3.org/2000/01/rdf-schema#label isoleucyl-tRNA synthetase
gptkbp:inhibitedBy mupirocin
gptkbp:location gptkb:cytoplasm
gptkbp:PDB 1FFY
gptkbp:product gptkb:AMP
pyrophosphate
isoleucyl-tRNA(Ile)
gptkbp:requires protein biosynthesis
gptkbp:structure multi-domain protein
gptkbp:substrate gptkb:ATP
gptkb:isoleucine
tRNA(Ile)
gptkbp:UniProt_ID_(E._coli) P00956
gptkbp:UniProtID P41252
gptkbp:bfsParent gptkb:class_I_aminoacyl-tRNA_synthetase
gptkbp:bfsLayer 7