Statements (17)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
IMP-type carbapenemase
|
| gptkbp:discoveredBy |
gptkb:Pseudomonas_aeruginosa
|
| gptkbp:encodedBy |
blaIMP gene
|
| gptkbp:firstReported |
1991
|
| gptkbp:foundIn |
gptkb:Enterobacteriaceae
gptkb:Acinetobacter_baumannii Pseudomonas species |
| gptkbp:function |
hydrolyzes carbapenem antibiotics
|
| https://www.w3.org/2000/01/rdf-schema#label |
imipenemase
|
| gptkbp:mechanismOfAction |
beta-lactamase activity
|
| gptkbp:proteinFamily |
class B metallo-beta-lactamase
|
| gptkbp:resistantTo |
gptkb:imipenem
other carbapenems |
| gptkbp:significance |
antibiotic resistance in Gram-negative bacteria
|
| gptkbp:bfsParent |
gptkb:antimicrobial_resistance_gene_IMP
|
| gptkbp:bfsLayer |
8
|