Statements (25)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
combination drug
|
| gptkbp:approvedBy |
1985
|
| gptkbp:ATCCode |
gptkb:J01DH51
|
| gptkbp:brand |
gptkb:Primaxin
|
| gptkbp:contraindication |
hypersensitivity to beta-lactams
|
| gptkbp:discoveredBy |
gptkb:Merck_&_Co.
|
| gptkbp:drugClass |
carbapenem antibiotic
dehydropeptidase inhibitor |
| gptkbp:FDAApproved |
yes
|
| https://www.w3.org/2000/01/rdf-schema#label |
imipenem and cilastatin
|
| gptkbp:includesDrug |
gptkb:cilastatin
gptkb:imipenem |
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits bacterial cell wall synthesis
cilastatin inhibits renal dehydropeptidase |
| gptkbp:pregnancyCategory |
C (US)
|
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
nausea
vomiting seizures rash |
| gptkbp:spectrumOfActivity |
broad-spectrum
|
| gptkbp:usedFor |
bacterial infections
|
| gptkbp:bfsParent |
gptkb:J01DH51
|
| gptkbp:bfsLayer |
6
|