human XPO1 gene

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:gene
gptkbp:alternativeName CRM1
gptkbp:associatedWith gptkb:acute_myeloid_leukemia
chronic lymphocytic leukemia
gptkbp:biologicalProcess nuclear export signal receptor activity
protein export from nucleus
gptkbp:cellularComponent gptkb:nucleus
gptkbp:discoveredIn 1997
gptkbp:encodes Exportin-1 protein
gptkbp:Entrez_Gene_ID 7514
ENSG00000122852
gptkbp:expressedIn various tissues
gptkbp:function mediates nuclear export of proteins and RNAs
gptkbp:geneType protein-coding
gptkbp:HGNC_ID 12823
https://www.w3.org/2000/01/rdf-schema#label human XPO1 gene
gptkbp:locatedOnChromosome chromosome 2
2p15
gptkbp:orthologInMouse Xpo1
gptkbp:targetOfDrug selinexor
gptkbp:UniProtID O14980
gptkbp:bfsParent gptkb:Exit2-DR_gene
gptkbp:bfsLayer 7