Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:alsoKnownAs |
gptkb:glucokinase
|
| gptkbp:biologicalProcess |
ATP binding
glucose binding |
| gptkbp:catalyzes |
phosphorylation of glucose to glucose-6-phosphate
|
| gptkbp:cofactor |
Mg2+
|
| gptkbp:discoveredBy |
gptkb:Earl_W._Sutherland_Jr.
|
| gptkbp:EC_number |
2.7.1.2
|
| gptkbp:expressedIn |
liver
pancreas |
| gptkbp:foundIn |
liver
pancreatic beta cells |
| gptkbp:gene |
gptkb:GCK
|
| https://www.w3.org/2000/01/rdf-schema#label |
hexokinase D
|
| gptkbp:Km_for_glucose |
high
|
| gptkbp:locatedOnChromosome |
7p15.3
|
| gptkbp:mutationAssociatedWith |
maturity onset diabetes of the young type 2
|
| gptkbp:product |
gptkb:ADP
gptkb:glucose-6-phosphate |
| gptkbp:regulates |
not inhibited by glucose-6-phosphate
|
| gptkbp:role |
glucose homeostasis
|
| gptkbp:structure |
monomeric
|
| gptkbp:substrate |
gptkb:ATP
glucose |
| gptkbp:bfsParent |
gptkb:HK3
|
| gptkbp:bfsLayer |
7
|