Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:drug
|
| gptkbp:bfsLayer |
8
|
| gptkbp:bfsParent |
gptkb:C._griseus
|
| gptkbp:activities |
inhibits fungal cell mitosis
|
| gptkbp:appointed_by |
oral medication
|
| gptkbp:approves |
gptkb:FDA
|
| gptkbp:brand |
Grifulvin V
Gris-PEG |
| gptkbp:clinical_trial |
Phase II
Phase III |
| gptkbp:contraindication |
porphyria
liver disease pregnancy hypersensitivity to griseofulvin |
| gptkbp:developed_by |
Penicillium griseofulvum
|
| gptkbp:discovered_by |
1939
|
| gptkbp:dosage_form |
gptkb:tablet
suspension |
| gptkbp:duration |
several weeks to months
|
| gptkbp:excretion |
urine
|
| https://www.w3.org/2000/01/rdf-schema#label |
griseofulvin
|
| gptkbp:indication |
gptkb:tinea_corporis
onychomycosis tinea pedis tinea capitis tinea cruris |
| gptkbp:interacts_with |
gptkb:warfarin
oral contraceptives barbiturates |
| gptkbp:is_available_on |
generic medication
|
| gptkbp:is_effective_against |
viral infections
bacterial infections varies by infection type |
| gptkbp:is_monitored_by |
liver function tests
complete blood count renal function tests |
| gptkbp:is_used_for |
treatment of fungal infections
|
| gptkbp:lifespan |
about 24 hours
|
| gptkbp:metabolism |
liver
|
| gptkbp:side_effect |
dizziness
fatigue headache nausea allergic reactions diarrhea liver toxicity skin rash photosensitivity |
| gptkbp:storage |
room temperature
protected from light |
| gptkbp:suitable_for |
patients with severe renal impairment
breastfeeding women children under 2 years patients with severe liver impairment |