|
gptkbp:instanceOf
|
gptkb:protein
gptkb:serine_protease
|
|
gptkbp:alternativeName
|
GzmK
Tryptase II
serine protease 3
|
|
gptkbp:associatedWith
|
immune response
|
|
gptkbp:biologicalProcess
|
serine-type endopeptidase activity
|
|
gptkbp:cleavesAfter
|
lysine residues
|
|
gptkbp:EC_number
|
3.4.21.63
|
|
gptkbp:encodedBy
|
gptkb:GZMK_gene
|
|
gptkbp:Entrez_Gene_ID
|
3003 (human)
|
|
gptkbp:expressedIn
|
gptkb:natural_killer_cells
cytotoxic T lymphocytes
|
|
gptkbp:foundIn
|
gptkb:human
gptkb:mouse
|
|
gptkbp:function
|
induces apoptosis in target cells
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
granzyme K
|
|
gptkbp:length
|
264 amino acids
|
|
gptkbp:locatedIn
|
cytoplasmic granules
|
|
gptkbp:locatedOnChromosome
|
chromosome 5q11-q12 (human)
|
|
gptkbp:mass
|
28 kDa
|
|
gptkbp:memberOf
|
granzyme family
|
|
gptkbp:orthologIn
|
gptkb:mouse
right
|
|
gptkbp:roleInImmunity
|
cell-mediated cytotoxicity
|
|
gptkbp:structure
|
contains serine protease domain
|
|
gptkbp:subcellularLocation
|
secretory granule lumen
|
|
gptkbp:UniProtID
|
P49862
|
|
gptkbp:bfsParent
|
gptkb:granzymes
|
|
gptkbp:bfsLayer
|
6
|