Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:PMEL
ME20-M Pmel17 Silver locus protein homolog |
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:PMEL_gene
|
| gptkbp:foundIn |
gptkb:melanocytes
|
| gptkbp:function |
melanin synthesis
melanosome biogenesis |
| https://www.w3.org/2000/01/rdf-schema#label |
gp100
|
| gptkbp:locatedOnChromosome |
chromosome 12q13.2 (human)
|
| gptkbp:relatedTo |
melanoma
pigmentation |
| gptkbp:species |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:structure |
type I transmembrane glycoprotein
|
| gptkbp:target |
T-cell based therapies
gp100 peptide vaccine |
| gptkbp:usedAs |
melanoma tumor antigen
|
| gptkbp:usedIn |
immunotherapy
|
| gptkbp:bfsParent |
gptkb:Kimmtrak
gptkb:PMEL |
| gptkbp:bfsLayer |
7
|