Statements (33)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
GARS1
GlyRS glycine--tRNA ligase |
gptkbp:associatedWith |
Charcot-Marie-Tooth disease type 2D
distal spinal muscular atrophy type V |
gptkbp:biologicalProcess |
translator
aminoacyl-tRNA biosynthesis glycine-tRNA ligase activity |
gptkbp:catalyzes |
attachment of glycine to tRNA(Gly)
|
gptkbp:EC_number |
6.1.1.14
|
gptkbp:family |
gptkb:class_II_aminoacyl-tRNA_synthetase
|
gptkbp:foundIn |
gptkb:Bacteria
archaea eukaryotes |
gptkbp:function |
aminoacylation of tRNA
|
gptkbp:gene |
GARS
|
https://www.w3.org/2000/01/rdf-schema#label |
glycyl-tRNA synthetase
|
gptkbp:locatedOnChromosome |
7p15
|
gptkbp:location |
gptkb:cytoplasm
mitochondria |
gptkbp:OMIM |
600287
|
gptkbp:product |
gptkb:AMP
pyrophosphate glycyl-tRNA(Gly) |
gptkbp:proteinFamily |
PF01411
|
gptkbp:requires |
gptkb:ATP
|
gptkbp:structure |
homodimer (in humans)
|
gptkbp:substrate |
glycine
tRNA(Gly) |
gptkbp:UniProtID |
P41250
|
gptkbp:bfsParent |
gptkb:class_II_aminoacyl-tRNA_synthetase
|
gptkbp:bfsLayer |
7
|