glycyl-tRNA synthetase

GPTKB entity

Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName GARS1
GlyRS
glycine--tRNA ligase
gptkbp:associatedWith Charcot-Marie-Tooth disease type 2D
distal spinal muscular atrophy type V
gptkbp:biologicalProcess translator
aminoacyl-tRNA biosynthesis
glycine-tRNA ligase activity
gptkbp:catalyzes attachment of glycine to tRNA(Gly)
gptkbp:EC_number 6.1.1.14
gptkbp:family gptkb:class_II_aminoacyl-tRNA_synthetase
gptkbp:foundIn gptkb:Bacteria
archaea
eukaryotes
gptkbp:function aminoacylation of tRNA
gptkbp:gene GARS
https://www.w3.org/2000/01/rdf-schema#label glycyl-tRNA synthetase
gptkbp:locatedOnChromosome 7p15
gptkbp:location gptkb:cytoplasm
mitochondria
gptkbp:OMIM 600287
gptkbp:product gptkb:AMP
pyrophosphate
glycyl-tRNA(Gly)
gptkbp:proteinFamily PF01411
gptkbp:requires gptkb:ATP
gptkbp:structure homodimer (in humans)
gptkbp:substrate glycine
tRNA(Gly)
gptkbp:UniProtID P41250
gptkbp:bfsParent gptkb:class_II_aminoacyl-tRNA_synthetase
gptkbp:bfsLayer 7