|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:activatedBy
|
gptkb:AMP
phosphorylase kinase
|
|
gptkbp:allosteric_site
|
AMP binding site
glucose binding site
|
|
gptkbp:alternativeName
|
brain phosphorylase
liver phosphorylase
myophosphorylase
|
|
gptkbp:CASNumber
|
9001-00-7
|
|
gptkbp:catalyzes
|
phosphorolysis of glycogen
|
|
gptkbp:cofactor
|
gptkb:pyridoxal_phosphate
|
|
gptkbp:discoveredBy
|
Carl and Gerty Cori
|
|
gptkbp:EC_number
|
2.4.1.1
|
|
gptkbp:enzymeClassification
|
gptkb:glycosyltransferase
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
liver
|
|
gptkbp:form
|
phosphorylase a
|
|
gptkbp:foundIn
|
gptkb:skeletal_muscle
liver
|
|
gptkbp:gene
|
gptkb:PYGB
gptkb:PYGL
gptkb:PYGM
|
|
gptkbp:inactive_form
|
phosphorylase b
|
|
gptkbp:inhibitedBy
|
gptkb:ATP
gptkb:CP-91149
gptkb:DAB_(1,4-dideoxy-1,4-imino-D-arabinitol)
gptkb:flavopiridol
gptkb:glucose-6-phosphate
caffeine
glucose
glucosamine
phosphoprotein phosphatase
|
|
gptkbp:molecularWeight
|
~97 kDa (monomer)
|
|
gptkbp:Nobel_Prize_related
|
gptkb:1947_Nobel_Prize_in_Physiology_or_Medicine
|
|
gptkbp:PDB
|
1GPB
|
|
gptkbp:product
|
glucose-1-phosphate
|
|
gptkbp:regulates
|
phosphorylation
allosteric effectors
|
|
gptkbp:role
|
energy metabolism
glycogenolysis
|
|
gptkbp:significance
|
gptkb:Hers_disease
gptkb:McArdle_disease
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:substrate
|
gptkb:glycogen
inorganic phosphate
|
|
gptkbp:UniProtID
|
P11217
|
|
gptkbp:bfsParent
|
gptkb:glycogen
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
glycogen phosphorylase
|