Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
class of drugs
|
| gptkbp:compatibleWith |
benzodiazepine
opioid |
| gptkbp:contraindication |
hypersensitivity to gabapentinoids
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:eliminatedIn |
renal
|
| gptkbp:example |
gptkb:gabapentin
gptkb:pregabalin mirogabalin |
| https://www.w3.org/2000/01/rdf-schema#label |
gabapentinoids
|
| gptkbp:mechanismOfAction |
bind to alpha-2-delta subunit of voltage-gated calcium channels
|
| gptkbp:metabolism |
minimal hepatic metabolism
|
| gptkbp:potentialForAbuse |
yes
|
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
dizziness
weight gain somnolence peripheral edema |
| gptkbp:usedFor |
epilepsy
peripheral neuropathy anxiety disorders |
| gptkbp:bfsParent |
gptkb:prurigo_nodularis
|
| gptkbp:bfsLayer |
7
|