Statements (52)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
antipsychotic medication
thioxanthene derivative |
| gptkbp:approvedBy |
1965
|
| gptkbp:ATCCode |
N05AF01
|
| gptkbp:availableOn |
oral tablet
long-acting injection |
| gptkbp:brand |
Depixol
Fluanxol |
| gptkbp:CASNumber |
2413-38-9
|
| gptkbp:chemicalFormula |
C23H25F3N2OS
|
| gptkbp:contraindication |
gptkb:pheochromocytoma
coma CNS depression hypersensitivity to thioxanthenes |
| gptkbp:developedBy |
gptkb:Lundbeck
|
| gptkbp:drugClass |
typical antipsychotic
|
| gptkbp:eliminationHalfLife |
35 hours (oral)
7-10 days (depot) |
| gptkbp:excretion |
urine
feces |
| gptkbp:hasEnantiomer |
cis-flupentixol
trans-flupentixol |
| https://www.w3.org/2000/01/rdf-schema#label |
flupentixol
|
| gptkbp:interactsWith |
gptkb:beer
gptkb:levodopa gptkb:CNS_depressants anticholinergics antihypertensives |
| gptkbp:KEGGID |
D07916
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
dopamine D2 receptor antagonist
serotonin receptor antagonist |
| gptkbp:metabolism |
liver
|
| gptkbp:pregnancyCategory |
gptkb:C_(Australia)
|
| gptkbp:PubChem_CID |
3373
CHEMBL1387 DB00875 |
| gptkbp:routeOfAdministration |
oral
intramuscular injection |
| gptkbp:sideEffect |
weight gain
insomnia drowsiness dry mouth extrapyramidal symptoms sexual dysfunction |
| gptkbp:synonym |
flupenthixol
|
| gptkbp:UNII |
Q2J1F44ZTI
|
| gptkbp:usedFor |
schizophrenia
psychosis depression (in some countries) |
| gptkbp:bfsParent |
gptkb:Melitracen
|
| gptkbp:bfsLayer |
7
|