|
gptkbp:instanceOf
|
gptkb:antipsychotic_medication
gptkb:thioxanthene_derivative
|
|
gptkbp:approvedBy
|
1965
|
|
gptkbp:ATCCode
|
N05AF01
|
|
gptkbp:availableOn
|
oral tablet
long-acting injection
|
|
gptkbp:brand
|
Depixol
Fluanxol
|
|
gptkbp:CASNumber
|
2413-38-9
|
|
gptkbp:chemicalFormula
|
C23H25F3N2OS
|
|
gptkbp:contraindication
|
gptkb:pheochromocytoma
coma
CNS depression
hypersensitivity to thioxanthenes
|
|
gptkbp:developedBy
|
gptkb:Lundbeck
|
|
gptkbp:drugClass
|
typical antipsychotic
|
|
gptkbp:eliminationHalfLife
|
35 hours (oral)
7-10 days (depot)
|
|
gptkbp:excretion
|
urine
feces
|
|
gptkbp:hasEnantiomer
|
cis-flupentixol
trans-flupentixol
|
|
gptkbp:interactsWith
|
gptkb:beer
gptkb:levodopa
gptkb:CNS_depressants
anticholinergics
antihypertensives
|
|
gptkbp:KEGGID
|
D07916
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
gptkb:serotonin_receptor_antagonist
dopamine D2 receptor antagonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:pregnancyCategory
|
gptkb:C_(Australia)
|
|
gptkbp:PubChem_CID
|
3373
CHEMBL1387
DB00875
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular injection
|
|
gptkbp:sideEffect
|
gptkb:sexual_dysfunction
weight gain
insomnia
drowsiness
dry mouth
extrapyramidal symptoms
|
|
gptkbp:synonym
|
flupenthixol
|
|
gptkbp:UNII
|
Q2J1F44ZTI
|
|
gptkbp:usedFor
|
schizophrenia
psychosis
depression (in some countries)
|
|
gptkbp:bfsParent
|
gptkb:Melitracen
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
flupentixol
|