|
gptkbp:instanceOf
|
gptkb:antibiotic
|
|
gptkbp:ATCCode
|
J01CF05
|
|
gptkbp:brand
|
Floxapen
Staphylex
|
|
gptkbp:CASNumber
|
5250-39-5
|
|
gptkbp:chemicalFormula
|
C19H17ClFN3O5S
|
|
gptkbp:contraindication
|
penicillin allergy
|
|
gptkbp:developedBy
|
1960s
|
|
gptkbp:discoveredBy
|
gptkb:Beecham
|
|
gptkbp:eliminationHalfLife
|
0.75-1 hour
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
flucloxacillin
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits bacterial cell wall synthesis
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:notEffectiveAgainst
|
gptkb:MRSA
|
|
gptkbp:pregnancyCategory
|
B1 (Australia)
|
|
gptkbp:relatedTo
|
gptkb:methicillin
gptkb:cloxacillin
gptkb:dicloxacillin
|
|
gptkbp:resistantTo
|
beta-lactamase
|
|
gptkbp:routeOfAdministration
|
oral
intramuscular
intravenous
|
|
gptkbp:sideEffect
|
nausea
diarrhea
rash
allergic reactions
liver dysfunction
|
|
gptkbp:spectrumOfActivity
|
Gram-positive bacteria
|
|
gptkbp:usedFor
|
gptkb:otitis_externa
skin infections
endocarditis
bacterial infections
respiratory tract infections
bone infections
joint infections
|
|
gptkbp:WHOModelListOfEssentialMedicines
|
true
|
|
gptkbp:bfsParent
|
gptkb:oxacillin
gptkb:6-APA_(6-aminopenicillanic_acid)
|
|
gptkbp:bfsLayer
|
7
|