Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:antibiotic
|
gptkbp:ATCCode |
gptkb:J01CF02
|
gptkbp:CASNumber |
61-72-3
|
gptkbp:contraindication |
hypersensitivity to penicillins
|
gptkbp:discoveredBy |
gptkb:Beecham
|
gptkbp:drugClass |
narrow-spectrum beta-lactam antibiotic
|
gptkbp:eliminationHalfLife |
30 minutes
|
gptkbp:excretion |
renal
biliary |
gptkbp:hasMolecularFormula |
gptkb:C19H18ClN3O5S
|
https://www.w3.org/2000/01/rdf-schema#label |
cloxacillin
|
gptkbp:introduced |
1960s
|
gptkbp:legalStatus |
prescription only
|
gptkbp:mechanismOfAction |
inhibits bacterial cell wall synthesis
|
gptkbp:notEffectiveAgainst |
gptkb:methicillin-resistant_Staphylococcus_aureus_(MRSA)
|
gptkbp:pregnancyCategory |
B (US)
|
gptkbp:resistantTo |
beta-lactamase
|
gptkbp:routeOfAdministration |
oral
intramuscular intravenous |
gptkbp:sideEffect |
rash
allergic reactions gastrointestinal upset liver dysfunction |
gptkbp:synonym |
gptkb:Cloxapen
gptkb:Orbenin |
gptkbp:usedFor |
bacterial infections
staphylococcal infections |
gptkbp:bfsParent |
gptkb:MSSA
|
gptkbp:bfsLayer |
6
|