Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
FBN1 protein
|
| gptkbp:associatedWith |
gptkb:Marfan_syndrome
|
| gptkbp:discoveredBy |
Franz R. E. Dietz
|
| gptkbp:domain |
EGF-like domain
TB (transforming growth factor beta-binding) domain calcium-binding EGF-like domain |
| gptkbp:encodedBy |
gptkb:FBN1_gene
|
| gptkbp:foundIn |
extracellular matrix
|
| gptkbp:function |
structural component of microfibrils
|
| https://www.w3.org/2000/01/rdf-schema#label |
fibrillin-1 precursor
|
| gptkbp:length |
2871 amino acids
|
| gptkbp:locatedOnChromosome |
15q21.1
|
| gptkbp:molecularWeight |
320 kDa
|
| gptkbp:mutationAssociatedWith |
connective tissue disorders
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Mus_musculus |
| gptkbp:postTranslationalModification |
glycosylation
cleavage to mature fibrillin-1 |
| gptkbp:UniProtID |
gptkb:P35555
|
| gptkbp:bfsParent |
gptkb:NP_000468.1
|
| gptkbp:bfsLayer |
8
|