fecal microbiota transplantation

GPTKB entity

Statements (29)
Predicate Object
gptkbp:instanceOf medical procedure
gptkbp:alsoKnownAs FMT
gptkbp:approvedBy FDA (for recurrent C. difficile infection)
gptkbp:category gptkb:disease
gastroenterology
gptkbp:contraindication immunocompromised patients (relative)
gptkbp:cookingMethod donor stool processed and filtered
gptkbp:donorScreening required to minimize risk of infection
gptkbp:effect high cure rate for recurrent C. difficile infection
gptkbp:firstDescribed 1958
https://www.w3.org/2000/01/rdf-schema#label fecal microbiota transplantation
gptkbp:mechanismOfAction restoration of healthy gut microbiota
gptkbp:method transplantation of fecal bacteria from a healthy donor to a patient
gptkbp:regulates regulated as a biologic in the US
gptkbp:relatedTo gptkb:antibiotic-associated_diarrhea
microbiome
probiotics
gptkbp:researchStatus ongoing clinical trials for other indications
gptkbp:riskFactor gastrointestinal symptoms
transmission of infectious agents
gptkbp:routeOfAdministration colonoscopy
enema
nasogastric tube
oral capsules
gptkbp:usedFor investigational treatment for irritable bowel syndrome
investigational treatment for inflammatory bowel disease
treatment of recurrent Clostridioides difficile infection
gptkbp:bfsParent gptkb:Clostridioides_difficile_infection
gptkbp:bfsLayer 5