familial Parkinson's disease
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
form of Parkinson's disease |
| gptkbp:affects |
central nervous system
|
| gptkbp:associatedWith |
gptkb:SNCA_gene_mutation
DJ-1 gene mutation LRRK2 gene mutation PARK2 gene mutation PINK1 gene mutation |
| gptkbp:causedBy |
genetic disorder
|
| gptkbp:field |
neurology
|
| gptkbp:firstDescribed |
early 20th century
|
| https://www.w3.org/2000/01/rdf-schema#label |
familial Parkinson's disease
|
| gptkbp:ICD-10_code |
gptkb:G20
|
| gptkbp:inheritance |
autosomal dominant
autosomal recessive |
| gptkbp:onset |
typically earlier than sporadic Parkinson's disease
|
| gptkbp:riskFactor |
family history of Parkinson's disease
|
| gptkbp:symptom |
bradykinesia
postural instability rigidity tremor |
| gptkbp:treatment |
gptkb:levodopa
deep brain stimulation dopamine agonists |
| gptkbp:bfsParent |
gptkb:LRRK2
gptkb:alpha-synuclein gptkb:SNCA gptkb:SNCA_gene_mutation |
| gptkbp:bfsLayer |
7
|