|
gptkbp:instanceOf
|
gptkb:drug
synthetic estrogen
|
|
gptkbp:ATCCode
|
G03CA01
|
|
gptkbp:brand
|
gptkb:Yaz
gptkb:Yasmin
gptkb:Alesse
gptkb:Apri
gptkb:Cilest
gptkb:Desogen
gptkb:Estinyl
gptkb:Femodene
gptkb:Kariva
gptkb:Levlen
gptkb:Mercilon
gptkb:Microgynon
gptkb:Mircette
gptkb:Nordette
gptkb:Norinyl
gptkb:Ortho-Novum
gptkb:Ortho_Tri-Cyclen
gptkb:Ovral
gptkb:Qlaira
gptkb:Seasonique
gptkb:Sprintec
gptkb:Tri-Sprintec
gptkb:TriNessa
gptkb:Zoely
gptkb:Zovia
gptkb:Loestrin
gptkb:NuvaRing
gptkb:Marvelon
gptkb:Evra
gptkb:Xulane
|
|
gptkbp:CASNumber
|
57-63-6
|
|
gptkbp:chemicalFormula
|
C20H24O2
|
|
gptkbp:contraindication
|
gptkb:cancer
gptkb:liver_disease
history of thromboembolic disorders
|
|
gptkbp:discoveredBy
|
gptkb:Hans_Herloff_Inhoffen
1938
|
|
gptkbp:eliminationHalfLife
|
13–27 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ethinyl estradiol
|
|
gptkbp:IUPACName
|
(17α)-19-norpregna-1,3,5(10)-trien-20-yne-3,17-diol
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
estrogen receptor agonist
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
296.4 g/mol
|
|
gptkbp:pregnancyCategory
|
X (contraindicated)
|
|
gptkbp:routeOfAdministration
|
oral
transdermal
vaginal
|
|
gptkbp:sideEffect
|
nausea
headache
hypertension
breast tenderness
increased risk of blood clots
|
|
gptkbp:synonym
|
gptkb:EE
gptkb:17α-ethynylestradiol
ethinylestradiol
|
|
gptkbp:used_in
|
oral contraceptive
hormone replacement therapy
|
|
gptkbp:bfsParent
|
gptkb:CYP3A4_gene
|
|
gptkbp:bfsLayer
|
6
|