17α-ethynylestradiol

URI: https://gptkb.org/entity/17α-ethynylestradiol

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:chemical_compound gptkb:synthetic_estrogen
gptkbp:affects	gptkb:sex_hormone-binding_globulin lipid metabolism estrogen receptor coagulation factors liver protein synthesis
gptkbp:ATCCode	G03CA01
gptkbp:CASNumber	57-63-6
gptkbp:category	gptkb:estrogen gptkb:phenol gptkb:secondary_alcohol gptkb:oral_contraceptive gptkb:hormonal_medication gptkb:Corticosteroid alkyne tertiary alcohol
gptkbp:chemicalFormula	C20H24O2
gptkbp:discoveredBy	gptkb:Hans_Herloff_Inhoffen 1938
gptkbp:eliminationHalfLife	13–27 hours
gptkbp:environmentalImpact	gptkb:endocrine_disruptor water pollutant
gptkbp:excretion	urine feces
gptkbp:IUPACName	(8R,9S,13S,14S,17R)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
gptkbp:meltingPoint	182–184 °C
gptkbp:MeSH_ID	D004967
gptkbp:metabolism	liver
gptkbp:molecularWeight	296.403 g/mol
gptkbp:PubChem_CID	5991 DB00977 CHEMBL1398
gptkbp:routeOfAdministration	oral transdermal vaginal
gptkbp:sideEffect	nausea headache increased risk of blood clots
gptkbp:synonym	ethinylestradiol EE2
gptkbp:UNII	423D2T571U
gptkbp:used_in	oral contraceptives
gptkbp:usedFor	hormone replacement therapy hormonal contraception
gptkbp:bfsParent	gptkb:ethinyl_estradiol
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	17α-ethynylestradiol