Statements (48)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
alkaloid
vasoconstrictor uterotonic agent |
| gptkbp:administeredBy |
oral
intramuscular injection intravenous injection |
| gptkbp:ATCCode |
G02AB03
|
| gptkbp:CASNumber |
60-79-7
|
| gptkbp:chemicalFormula |
C19H23N3O2
|
| gptkbp:contraindication |
hypertension
ischemic heart disease pre-eclampsia |
| gptkbp:discoveredBy |
gptkb:Dale_and_Laidlaw
|
| gptkbp:discoveredIn |
1935
|
| gptkbp:effect |
vasoconstriction
induces uterine contractions |
| gptkbp:eliminatedIn |
renal
|
| gptkbp:excretion |
urine
|
| gptkbp:foundIn |
gptkb:Claviceps_purpurea
|
| gptkbp:has_stereochemistry |
(R)-configuration at C-9
|
| https://www.w3.org/2000/01/rdf-schema#label |
ergonovine
|
| gptkbp:IUPACName |
(6aR,9R)-N-[(2S)-1-hydroxypropan-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
|
| gptkbp:KEGGID |
D07913
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:meltingPoint |
165–169 °C
|
| gptkbp:MeSH_ID |
D004841
|
| gptkbp:metabolism |
liver
|
| gptkbp:molecularWeight |
325.41 g/mol
|
| gptkbp:origin |
natural product
|
| gptkbp:pregnancyCategory |
contraindicated
|
| gptkbp:PubChem_CID |
8223
CHEMBL1201207 DB01253 CHEBI:4781 |
| gptkbp:sideEffect |
nausea
vomiting headache hypertension |
| gptkbp:synonym |
gptkb:ergometrine
ergobasine ergonovin |
| gptkbp:UNII |
6T84R30KC1
|
| gptkbp:usedAs |
diagnostic agent for variant angina
|
| gptkbp:usedFor |
prevention of postpartum hemorrhage
treatment of postpartum hemorrhage |
| gptkbp:usedIn |
obstetrics
|
| gptkbp:bfsParent |
gptkb:alkaloid
|
| gptkbp:bfsLayer |
6
|