|
gptkbp:instanceOf
|
gptkb:vasoconstrictor
gptkb:alkaloid
gptkb:uterotonic_agent
|
|
gptkbp:administeredBy
|
oral
intramuscular injection
intravenous injection
|
|
gptkbp:ATCCode
|
G02AB03
|
|
gptkbp:CASNumber
|
60-79-7
|
|
gptkbp:chemicalFormula
|
C19H23N3O2
|
|
gptkbp:contraindication
|
hypertension
ischemic heart disease
pre-eclampsia
|
|
gptkbp:discoveredBy
|
gptkb:Dale_and_Laidlaw
|
|
gptkbp:discoveredIn
|
1935
|
|
gptkbp:effect
|
vasoconstriction
induces uterine contractions
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:excretion
|
urine
|
|
gptkbp:foundIn
|
gptkb:Claviceps_purpurea
|
|
gptkbp:has_stereochemistry
|
(R)-configuration at C-9
|
|
gptkbp:IUPACName
|
(6aR,9R)-N-[(2S)-1-hydroxypropan-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
|
|
gptkbp:KEGGID
|
D07913
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:meltingPoint
|
165–169 °C
|
|
gptkbp:MeSH_ID
|
D004841
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
325.41 g/mol
|
|
gptkbp:origin
|
gptkb:natural_product
|
|
gptkbp:pregnancyCategory
|
contraindicated
|
|
gptkbp:PubChem_CID
|
8223
CHEMBL1201207
DB01253
CHEBI:4781
|
|
gptkbp:sideEffect
|
nausea
vomiting
headache
hypertension
|
|
gptkbp:synonym
|
gptkb:ergometrine
ergobasine
ergonovin
|
|
gptkbp:UNII
|
6T84R30KC1
|
|
gptkbp:usedAs
|
diagnostic agent for variant angina
|
|
gptkbp:usedFor
|
prevention of postpartum hemorrhage
treatment of postpartum hemorrhage
|
|
gptkbp:usedIn
|
obstetrics
|
|
gptkbp:bfsParent
|
gptkb:ergometrine
|
|
gptkbp:bfsLayer
|
9
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ergonovine
|