Statements (19)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:drug
small molecule |
gptkbp:ATCCode |
none
|
gptkbp:CASNumber |
1204669-58-8
|
gptkbp:chemicalFormula |
C11H13BrFN7O4S
|
gptkbp:clinicalTrialPhase |
Phase III (as of 2018)
|
gptkbp:developedBy |
gptkb:Incyte_Corporation
|
gptkbp:failedLaunches |
gptkb:ECHO-301/KEYNOTE-252_trial
|
https://www.w3.org/2000/01/rdf-schema#label |
epacadostat
|
gptkbp:intendedUse |
immunotherapy
|
gptkbp:isInvestigational |
true
|
gptkbp:IUPACName |
N-(3-bromo-1H-indazol-6-yl)-6-fluoro-3-(pyridin-2-ylmethylamino)pyridine-2-carboxamide
|
gptkbp:mechanismOfAction |
IDO1 inhibitor
|
gptkbp:molecularWeight |
456.23 g/mol
|
gptkbp:routeOfAdministration |
oral
|
gptkbp:synonym |
gptkb:INCB024360
|
gptkbp:target |
gptkb:indoleamine_2,3-dioxygenase_1
|
gptkbp:bfsParent |
gptkb:IDO1
|
gptkbp:bfsLayer |
7
|